期刊
JOURNAL OF RHEUMATOLOGY
卷 45, 期 11, 页码 1509-1514出版社
J RHEUMATOL PUBL CO
DOI: 10.3899/jrheum.171314
关键词
CONNECTIVE TISSUE DISEASES; INTERSTITIAL LUNG DISEASE; PULMONARY FIBROSIS; RHEUMATIC DISEASES
类别
Objective. Interstitial lung diseases (ILD) form a diverse group of parenchymal lung disorders. Currently, a multidisciplinary team (MDT) including pulmonologists, radiologists, and pathologists is the gold standard for ILD diagnosis. Recently, additional subtypes of connective tissue disease (CTD)-ILD with autoimmune features were defined, making the rheumatological assessment increasingly important. We aimed to assess the effect of adding a rheumatologist to the MDT for routine rheumatology assessment. Methods. A prospective study that assessed newly diagnosed ILD patients by 2 parallel blinded arms; all patients were evaluated by both MDT (e.g., history, physical examination, blood tests, pulmonary function tests, and biopsies, if needed) and a rheumatologist (e.g., history, physical examination, blood and serological tests). Results. Sixty patients were assessed with the mean age of 67.3 +/- 12 years, 55% male, and 28% smokers. The rheumatological assessment reclassified 21% of the idiopathic pulmonary fibrosis as CTD. Moreover, the number of CTD-ILD with autoimmune features was increased by 77%. These included antineutrophil cytoplasmic antibody-associated vasculitis, antisynthetase syndrome, and IgG4-related ILD. Retrospectively, rheumatological evaluation could have saved 7 bronchoscopies and 1 surgical biopsy. Conclusion. Adding routine rheumatology assessments could significantly increase diagnostic accuracy and reduce invasive procedures.
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