期刊
PHYTOCHEMISTRY LETTERS
卷 14, 期 -, 页码 234-238出版社
ELSEVIER
DOI: 10.1016/j.phytol.2015.10.020
关键词
Trichilia connaroides; Meliaceae; Limonoids; Nitric oxide production inhibition
资金
- Hundred Talents Program of the Chinese Academy of Sciences [Y3ZK101B01]
- 135 Programs of Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences [XTBG-F02]
- Yunnan Province, National Natural Science Union Foundation of China [NSFC-U1302222]
Two new rearranged limonoids, trichiliton I (1) and 12-deacetoxyltrijugin A (2) along with four previously reported compounds (3-6) were isolated from the roots of Trichilia connaroides. Their structures were established on the basis of extensive spectroscopic analysis including HR-ESI-MS and 1D and 2D NMR. The new compounds 1 and 2 exhibited weak inhibitory effects on lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 cells in a dose-dependent manner. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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