期刊
JOURNAL OF PSYCHOSOMATIC RESEARCH
卷 76, 期 3, 页码 207-212出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jpsychores.2013.12.012
关键词
Cancer; Psychiatry; Mental disorder; Epidemiology
类别
资金
- National Institute of Mental Health (NIMH) [R01 MH070884, U01-MH60220]
- John D. and Catherine T. MacArthur Foundation
- Pfizer Foundation
- US Public Health Service [R13-MH066849, R01-MH069864, R01 DA016558]
- Fogarty International Center [FIRCA R03-TW006481]
- Pan American Health Organization
- Eli Lilly and Company
- Ortho-McNeil Pharmaceutical
- GlaxoSmithKline
- Bristol-Myers Squibb
- Ministry of Social Protection
- Saldarriaga Concha Foundation
- European Commission [QLG5-1999-01042, SANCO 2004123, EAHC 20081308]
- Piedmont Region (Italy)
- Fondo de Investigacion Sanitaria, Instituto de Salud Carlos III, Spain [FIS 00/0028]
- Ministerio de Ciencia y Tecnologia, Spain [SAF 2000-158-CE]
- Departament de Salut, Generalitat de Catalunya, Spain, Instituto de Salud Carlos III [CIBER CB06/02/0046, RETICS RD06/0011 REM-TAP]
- Grant for Research on Psychiatric and Neurological Diseases and Mental Health from the Japan Ministry of Health, Labour and Welfare [H13-SHOGAI-023, H14-TOKUBETSU-026, H16-KOKORO-013]
- National Institute of Psychiatry Ramon de la Fuente [INPRFMDIES 4280]
- National Council on Science and Technology [CONACyT-G30544-H]
- PanAmerican Health Organization (PAHO)
- National Institute of Health of the Ministry of Health of Peru
- Norwegian Financial Mechanism
- European Economic Area Mechanism
- olish Ministry of Health
- Shenzhen Bureau of Health
- Shenzhen Bureau of Science, Technology, and Information
- Iraqi IMHS team
- Japanese and European Funds through the United Nations Development Group Iraq Trust Fund (UNDG IF)
- Ministry of Health
- Israel National Institute for Health Policy and Health Services Research
- National Insurance Institute of Israel
- New Zealand Ministry of Health, Alcohol Advisory Council
- Health Research Council
- Champalimaud Foundation
- Gulbenldan Foundation
- Foundation for Science and Technology (FCT)
- National Institute of Drug Abuse (NIDA)
- Substance Abuse and Mental Health Services Administration (SAMHSA)
- Robert Wood Johnson Foundation (RWJF) [044708]
- John W. Alden Trust
Objective: The associations between mental disorders and cancer remain unclear. It is also unknown whether any associations vary according to life stage or gender. This paper examines these research questions using data from the World Mental Health Survey Initiative. Methods: The World Health Organization Composite International Diagnostic Interview retrospectively assessed the lifetime prevalence of 16 DSM-IV mental disorders in face-to-face household population surveys in nineteen countries (n = 52,095). Cancer was indicated by self-report of diagnosis. Smoking was assessed in questions about current and past tobacco use. Survival analyses estimated associations between first onset of mental disorders and subsequently reported cancer. Results: After adjustment for comorbidity, panic disorder, specific phobia and alcohol abuse were associated with a subsequently self-reported diagnosis of cancer. There was an association between number of mental disorders and the likelihood of reporting a cancer diagnosis following the onset of the mental disorder. This suggests that the associations between mental disorders and cancer risk may be generalised, rather than specific to a particular disorder. Depression is more strongly associated with self-reported cancers diagnosed early in life and in women. PTSD is also associated with cancers diagnosed early in life. Conclusion: This study reports the magnitude of the associations between mental disorders and a self-reported diagnosis of cancer and provides information about the relevance of comorbidity, gender and the impact at different stages of life. The findings point to a link between the two conditions and lend support to arguments for early identification and treatment of mental disorders. (C) 2014 Elsevier Inc All rights reserved.
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