期刊
JOURNAL OF PSYCHOSOMATIC RESEARCH
卷 73, 期 3, 页码 163-168出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jpsychores.2012.06.001
关键词
Coronary artery disease; Depression; PHQ-8; PHQ-9; Suicide
类别
资金
- McGill University Faculty of Medicine Alexander McFee Fellowship Award
- National Center for Complementary and Alternative Medicine [R24AT004641]
- Miller Family Scholar Program of the Johns Hopkins Center for Innovative Medicine
- Canadian Institutes of Health Research
- Etablissement de Jeunes Chercheurs award from the Fonds de la Recherche en Sante Quebec
- Department of Veterans Affairs, Washington, DC
- National Heart Lung and Blood Institute, Bethesda, MD [R01 HL079235]
- American Federation for Aging Research, New York, NY
- Robert Wood Johnson Foundation (Faculty Scholars Program), Princeton, NJ
- Ischemia Research and Education Foundation, South San Francisco, CA
Objective: Item 9 of the Patient Health Questionnaire-9 (PHQ-9), which inquires about both passive thoughts of death and active ideas of self-harm, has been used to assess suicide risk. The objectives of this study were (1) to determine the proportion of patients who responded yes to Item 9 who endorsed active suicidal ideation in response to more direct questions from a structured clinical interview and (2) to compare the sensitivity and specificity for detecting cases of depression of the PHQ-9 and the PHQ-8, which does not include Item 9, as well as the correlation between the PHQ-8 and PHQ-9. Methods: Coronary artery disease (CAD) outpatients were administered the PHQ-9 and the Computerized Diagnostic Interview Schedule (C-DIS). Item 9 responses were compared to suicidal ideation and intent in the last year based on the C-DIS. Scores on the PHQ-8 were obtained by eliminating Item 9 from the PHQ-9. Test characteristics of the PHQ-9 and PHQ-8 were compared. Results: Of 1022 patients, 110 (10.8%) endorsed Item 9. Of those, only 22 (19.8%) reported thoughts about committing suicide, and only 9 of those (8.1%) reported a suicide plan any time in the last year based on the C-DIS. Correlation between PHQ-9 and PHQ-8 scores was r=0.997. Sensitivity and specificity for the PHQ-9 (54%, 90%) and PHQ-8 (50%, 91%) to detect major depression were similar. Conclusion: Item 9 does not appear to be an accurate suicide screen. The PHQ-8 may be a better option than the PHQ-9 in CAD patients. (C) 2012 Elsevier Inc. All rights reserved.
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