期刊
JOURNAL OF PROTEOMICS
卷 75, 期 14, 页码 4251-4258出版社
ELSEVIER
DOI: 10.1016/j.jprot.2012.05.007
关键词
Farm animals; Nutrition; Proteomics; Ruminants; Saliva
资金
- FCT - Fundacao para a Ciencia e a Tecnologia - Science and Technology Foundation (Lisbon, Portugal) of the Ministry of Science, Technology and Higher Education [SFRH/BPD/63240/2009]
- FEDER Funds through the Operational Programme for Competitiveness Factors - COMPETE
- National Funds through FCT - Foundation for Science and Technology under the Strategic Project [PEst-C/AGR/UI0115/2011, PEst-C/QUI/UI0062/2011]
- German Research Foundation (DFG) [SU124/15-1]
- Fundação para a Ciência e a Tecnologia [SFRH/BPD/63240/2009] Funding Source: FCT
Saliva is an extraordinary fluid in terms of research and diagnostic possibilities. Its composition in electrolytes, hormones and especially its proteome contains information about feeding status, nutritional requirements and adaptations to diet and environment, and also about health status of animals. It is easy to collect on a non-invasive and routine basis without any need for special training. Therefore, the analysis of salivary proteomes is going to emerge into a field of high interest with the future goal to maintain and improve livestock productivity and welfare. Moreover, the comprehensive analysis and identification of salivary proteins and peptides in whole and glandular saliva is a necessary pre-requisite to identify animal disease biomarkers and a powerful tool to better understand animal physiology. This review focuses on the different approaches used to study the salivary proteomes of farm animals, in respect to the physiology of nutrition and food perception in relation to food choices. The potential of animal saliva as a source of disease biomarkers will also be pointed out. Special emphasis is laid on the 'ruminating triad' - cattle, goat and sheep - as well as swine as major species of animal production in Western and Southern Europe. This article is part of a Special Issue entitled: Farm animal proteomics. (c) 2012 Elsevier B.V. All rights reserved.
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