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Working against our endogenous circadian clock: Breast cancer and electric lighting in the modern world
Richard G. Stevens
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2009)
Circadian disruption accelerates liver carcinogenesis in mice
Elisabeth Filipski et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2009)
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
Valeriya Lyssenko et al.
NATURE GENETICS (2009)
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk
Nabila Bouatia-Naji et al.
NATURE GENETICS (2009)
Circadian Rhythm of Clock Genes in Human Adipose Explants
Cecilia Gomez-Santos et al.
OBESITY (2009)
Effects of Nocturnal Light on (Clock) Gene Expression in Peripheral Organs: A Role for the Autonomic Innervation of the Liver
Cathy Cailotto et al.
PLOS ONE (2009)
JNK1 Phosphorylates SIRT1 and Promotes Its Enzymatic Activity
Nargis Nasrin et al.
PLOS ONE (2009)
Pathophysiology of depression: Role of sleep and the melatonergic system
Venkataramanujan Srinivasan et al.
PSYCHIATRY RESEARCH (2009)
Role of melatonin in metabolic regulation
Ahmet Korkmaz et al.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2009)
Shift work, chronodisruption and cancer?-the IARC 2007 challenge for research and prevention and 10 theses from the Cologne Colloquium 2008
Thomas C. Erren et al.
SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH (2009)
Daily Electrical Silencing in the Mammalian Circadian Clock
Mino D. C. Belle et al.
SCIENCE (2009)
Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1
Yasukazu Nakahata et al.
SCIENCE (2009)
A Circadian Loop asSIRTs Itself
Herman Wijnen
SCIENCE (2009)
Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD(+) Biosynthesis
Kathryn Moynihan Ramsey et al.
SCIENCE (2009)
Disturbance of circadian gene expression in breast cancer
Shou-Jen Kuo et al.
VIRCHOWS ARCHIV (2009)
The effect of melatonergic and non-melatonergic antidepressants on sleep: weighing the alternatives
Seithikurippu R. Pandi-Perumal et al.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY (2009)
Metabolism and cancer: the circadian clock connection
Saurabh Sahar et al.
NATURE REVIEWS CANCER (2009)
Shift work and cancer Risk, compensation, challenges
Thomas C. Erren et al.
BRITISH MEDICAL JOURNAL (2009)
Clock Genes May Influence Bipolar Disorder Susceptibility and Dysfunctional Circadian Rhythm
Jiajun Shi et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2008)
Genome-Wide Association Scan of Quantitative Traits for Attention Deficit Hyperactivity Disorder Identifies Novel Associations and Confirms Candidate Gene Associations
Jessica Lasky-Su et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2008)
Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression
Molly S. Bray et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2008)
Transcriptional activation of HIF-1 by RORα and its role in hypoxia signaling
Eun-Jin Kim et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2008)
The relation of exposure to shift work with atherosclerosis and myocardial infarction in a general population
Christiane M. Haupt et al.
ATHEROSCLEROSIS (2008)
Circadian regulation of response to oxidative stress in Drosophila melanogaster
Natraj Krishnan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
The circadian clock system in the mammalian retina
Gianluca Tosini et al.
BIOESSAYS (2008)
Circadian photoreception: ageing and the eye's important role in systemic health
P. L. Turner et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2008)
High Expression of Circadian Gene mPer2 Diminishes Radiosensitivity of Tumor Cells
Jing Zhang et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2008)
SIRT1 is a circadian deacetylase for core clock components
William J. Belden et al.
CELL (2008)
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
Yasukazu Nakahata et al.
CELL (2008)
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
Gad Asher et al.
CELL (2008)
Mitochondria - A nexus for aging, calorie restriction, and sirtuins?
Leonard Guarente
CELL (2008)
JNK2-dependent regulation of SIRT1 protein stability
Jack Ford et al.
CELL CYCLE (2008)
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons
Ying Li et al.
CELL METABOLISM (2008)
Melatonin, hormone of darkness and more - occurrence, control mechanisms, actions and bioactive metabolites
R. Hardeland
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Clock gene expression in adult primate suprachiasmatic nuclei and adrenal:: Is the adrenal a peripheral clock responsive to melatonin?
F. J. Valenzuela et al.
ENDOCRINOLOGY (2008)
Rhythmic expression of functional MT1 melatonin receptors in the rat adrenal gland
Hans G. Richter et al.
ENDOCRINOLOGY (2008)
Assessment of cardiovascular risk in shift healthcare workers
Alfredo Copertaro et al.
EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION (2008)
Effects of light cues on re-entrainment of the food-dominated peripheral clocks in mammals
Tao Wu et al.
GENE (2008)
Night-time work predisposes to non-Hodgkin lymphoma
Tuuli A. Lahti et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
The PDZ protein MUPP1 promotes Gi coupling and signaling of the Mt1 melatonin receptor
Jean-Luc Guillaume et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Melatonin and the circadian entrainment of metabolic and hormonal activities in primary isolated adipocytes
Maria Isabel Cardoso Alonso-Vale et al.
JOURNAL OF PINEAL RESEARCH (2008)
The antiproliferative activity of melatonin in B65 rat dopaminergic neuroblastoma cells is related to the downregulation of cell cycle-related genes
Javier G. Pizarro et al.
JOURNAL OF PINEAL RESEARCH (2008)
Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance
Chun W. Tam et al.
JOURNAL OF PINEAL RESEARCH (2008)
Effects of exogenous melatonin and circadian synchronization on tumor progression in melanoma-bearing C57BL6 mice
B. B. Otalora et al.
JOURNAL OF PINEAL RESEARCH (2008)
Evaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model
Javier Gutierrez-Cuesta et al.
JOURNAL OF PINEAL RESEARCH (2008)
Function and expression of melatonin receptors on human pancreatic islets
Reshma D. Ramraeheya et al.
JOURNAL OF PINEAL RESEARCH (2008)
Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic β-cells
Ina Stumpf et al.
JOURNAL OF PINEAL RESEARCH (2008)
The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response
Aaron E. Hoffman et al.
MOLECULAR CANCER RESEARCH (2008)
Period 2 Mutation Accelerates ApcMin/+ Tumorigenesis
Patricia A. Wood et al.
MOLECULAR CANCER RESEARCH (2008)
A length polymorphism in the circadian clock gene Per3 influences age at onset of bipolar disorder
Francesco Benedetti et al.
NEUROSCIENCE LETTERS (2008)
Investigation of 3111T/C polymorphism of the CLOCK gene in obese individuals with or without binge eating disorder:: Association with higher body mass index
Palmiero Monteleone et al.
NEUROSCIENCE LETTERS (2008)
SIRT1 Overexpression Antagonizes Cellular Senescence with Activated ERK/S6k1 Signaling in Human Diploid Fibroblasts
Jing Huang et al.
PLOS ONE (2008)
Polymorphisms within the Novel Type 2 Diabetes Risk Locus MTNR1B Determine β-Cell Function
Harald Staiger et al.
PLOS ONE (2008)
Physiological significance of a peripheral tissue circadian clock
Katja A. Lamia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
An Autonomous Circadian Clock in the Inner Mouse Retina Regulated by Dopamine and GABA
Guo-Xiang Ruan et al.
PLOS BIOLOGY (2008)
Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man
E. M. Scott et al.
INTERNATIONAL JOURNAL OF OBESITY (2008)
Non-synonymous polymorphisms in the circadian gene NPAS2 and breast cancer risk
Yong Zhu et al.
BREAST CANCER RESEARCH AND TREATMENT (2008)
Variants in circadian genes and prostate cancer risk: a population-based study in China
L. W. Chu et al.
PROSTATE CANCER AND PROSTATIC DISEASES (2008)
Abnormal melatonin synthesis in autism spectrum disorders
J. Melke et al.
MOLECULAR PSYCHIATRY (2008)
Live to the rhythm, slave to the rhythm
Eus J. W. Van Someren et al.
SLEEP MEDICINE REVIEWS (2007)
Is ASMT a susceptibility gene for autism spectrum disorders?: A replication study in European populations
C. Toma et al.
MOLECULAR PSYCHIATRY (2007)
Circadian clocks: regulators of endocrine and metabolic rhythms
Michael Hastings et al.
JOURNAL OF ENDOCRINOLOGY (2007)
Study of shift work and risk of coronary events
T. Ellingsen et al.
JOURNAL OF THE ROYAL SOCIETY FOR THE PROMOTION OF HEALTH (2007)
Impact of melatonin receptors on pCREB and clock-gene protein levels in the murine retina
Virginie Dinet et al.
CELL AND TISSUE RESEARCH (2007)
Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes
Peng Y. Woon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Inhibition of tumorigenesis by intratumoral delivery of the circadian gene mPer2 in C57BL/6 mice
H. Hua et al.
CANCER GENE THERAPY (2007)
Potential role for peripheral circadian clock dyssynchrony in the pathogenesis of cardiovascular dysfunction
Martin E. Young et al.
SLEEP MEDICINE (2007)
Intrinsic circadian clock of the mammalian retina: Importance for retinal processing of visual information
Kai-Florian Storch et al.
CELL (2007)
Uncoupling of promoter methylation and expression of Period1 in cervical cancer cells
Min-Chuan Hsu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Regulation of genes of the circadian clock in human colon cancer:: Reduced period-1 and dihydropyrimidine dehydrogenase transcription correlates in high-grade tumors
Walter Krugluger et al.
CANCER RESEARCH (2007)
Cadmium-induced changes in Per 1 and Per 2 gene expression in rat hypothalamus and anterior pituitary: Effect of melatonin
Pilar Cano et al.
TOXICOLOGY LETTERS (2007)
Melatonin receptor 1B (MTNR1B) gene polymorphism is associated with the occurrence of adolescent idiopathic scoliosis
Xu Sheng Qiu et al.
SPINE (2007)
Circadian clock and breast cancer - A molecular link
Saurabh Sahar et al.
CELL CYCLE (2007)
Association of Per1 and Npas2 with autistic disorder:: support for the clock genes/social timing hypothesis
B. Nicholas et al.
MOLECULAR PSYCHIATRY (2007)
Behavioral characterization and modulation of circadian rhythms by light and melatonin in C3H/HeN mice homozygous for the RORβ knockout
Monica I. Masana et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2007)
A role of the circadian system and circadian proteins in aging
Roman V. Kondratov
AGEING RESEARCH REVIEWS (2007)
Purification and identification of G protein-coupled receptor protein complexes under native conditions
Avais M. Daulat et al.
MOLECULAR & CELLULAR PROTEOMICS (2007)
Resveratrol stimulates AMP kinase activity in neurons
Biplab Dasgupta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Looking for the keys to diurnality downstream from the circadian clock:: role of melatonin in a dual-phasing rodent, Octodon degus
P. Vivanco et al.
JOURNAL OF PINEAL RESEARCH (2007)
The human Tim/Tipin complex coordinates an intra-S checkpoint response to UV that slows replication fork displacement
Keziban Unsal-Kacmaz et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Melatonin and type 2 diabetes -: a possible link?
Elmar Peschke et al.
JOURNAL OF PINEAL RESEARCH (2007)
CLOCK gene T3111C polymorphism is associated with Japanese schizophrenics: A preliminary study
T. Takao et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2007)
Epigenetic silencing of the candidate tumor suppressor gene Per1 in non-small cell lung cancer
Sigal Gery et al.
CLINICAL CANCER RESEARCH (2007)
Arylalkylamine N-acetyltransferase:: the timezyme
David C. Klein
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock
Benoit Kornmann et al.
PLOS BIOLOGY (2007)
Melatonin affects nuclear orphan receptors mRNA in the rat suprachiasmatic nuclei
L. Agez et al.
NEUROSCIENCE (2007)
Ala394Thr polymorphism in the clock gene NPAS2: A circadian modifier for the risk of non-Hodgkin's lymphoma
Yong Zhu et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Melatonin induces gene-specific effects on rhythmic mRNA expression in the pars tuberalis of the Siberian hamster (Phodopus sungorus)
Gabriela C. Wagner et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Three circadian clock genes Per2, Arnt1, and Npas2 contribute to winter depression
Timo Partonen et al.
ANNALS OF MEDICINE (2007)
A sense of time: how molecular clocks organize metabolism
Akira Kohsaka et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2007)
Euchronism, allochronism, and dyschronism: Is internal desynchronization of human circadian rhythms a sign of illness?
Alain E. Reinberg et al.
CHRONOBIOLOGY INTERNATIONAL (2007)
Clock gene expression in the retina of melatonin-proficient (C3H) and melatonin-deficient (C57BL) mice
Virginie Dinet et al.
JOURNAL OF PINEAL RESEARCH (2007)
Signaling mechanisms of melatonin in antiproliferation of hormone-refractory 22Rv1 human prostate cancer cells: implications for prostate cancer chemoprevention
Chun W. Tam et al.
JOURNAL OF PINEAL RESEARCH (2007)
Disturbance and strategies for reactivation of the circadian rhythm system in aging and Alzheimer's disease
Ying-Hui Wu et al.
SLEEP MEDICINE (2007)
Downregulation of circadian clock genes in chronic myeloid leukemia:: Alternative methylation pattern of hPER3
Ming-Yu Yang et al.
CANCER SCIENCE (2006)
Therapeutic treatments potentially mediated by melatonin receptors: potential clinical uses in the prevention of osteoporosis, cancer and as an adjuvant therapy
Paula A. Witt-Enderby et al.
JOURNAL OF PINEAL RESEARCH (2006)
CLOCK leaves its mark on histones
William J. Belden et al.
TRENDS IN BIOCHEMICAL SCIENCES (2006)
Pineal clock gene oscillation is disturbed in Alzheimer's disease, due to functional disconnection from the master clock
Ying-Hui Wu et al.
FASEB JOURNAL (2006)
Intermittent and rhythmic exposure to melatonin in primary cultured adipocytes enhances the insulin and dexamethasone effects on leptin expression
Maria Isabel Cardoso Alonso-Vale et al.
JOURNAL OF PINEAL RESEARCH (2006)
Peroxisome proliferator-activated receptor γ as a molecular target of resveratrol-induced modulation of polyamine metabolism
Sandra Ulrich et al.
CANCER RESEARCH (2006)
Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock
Roman V. Kondratov et al.
GENES & DEVELOPMENT (2006)
The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization
Angelique Levoye et al.
EMBO JOURNAL (2006)
Melatonin - Nature's most versatile biological signal?
S. R. Pandi-Perumal et al.
FEBS JOURNAL (2006)
Pinealectomy does not affect diurnal PER2 expression in the rat limbic forebrain
S Amir et al.
NEUROSCIENCE LETTERS (2006)
Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder
CM Nievergelt et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2006)
Association study of eight circadian genes with bipolar I disorder, schizoaffective disorder and schizophrenia
HA Mansour et al.
GENES BRAIN AND BEHAVIOR (2006)
Melatonin receptor (MT1) knockout mice display depression-like behaviors and deficits in sensorimotor gating
ZM Weil et al.
BRAIN RESEARCH BULLETIN (2006)
Multiple effects of melatonin on rhythmic clock gene expression in the mammalian pars tuberalis
JD Johnston et al.
ENDOCRINOLOGY (2006)
Intracellular signaling pathways involved in the cell growth inhibition of glioma cells by melatonin
V Martín et al.
CANCER RESEARCH (2006)
The circadian clock within the heart: potential influence on myocardial gene expression, metabolism, and function
ME Young
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Melatonin in mood disorders
Venkataramanujan Srinivasan et al.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY (2006)
Estrogen-signaling pathway: A link between breast cancer and melatonin oncostatic actions
Samuel Cos et al.
CANCER DETECTION AND PREVENTION (2006)
Immunocytochemical demonstration of day/night changes of clock gene protein levels in the murine adrenal gland: differences between melatonin-proficient (C3H) and melatonin-deficient (C57BL) mice
C Torres-Farfan et al.
JOURNAL OF PINEAL RESEARCH (2006)
Melatonin in the multi-oscillatory mammalian circadian world
P Pevet et al.
CHRONOBIOLOGY INTERNATIONAL (2006)
FoxO-dependent and -independent mechanisms mediate SirT1 effects on IGFBP-1 gene expression
LX Gan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Cardiac autonomic imbalance in female nurses with shift work
N Ishii et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2005)
Transcription profiling of C/EBP targets identifies Per2 as a gene implicated in myeloid leukemia
S Gery et al.
BLOOD (2005)
The temporal order of mammals. Evidence for multiple central and peripheral control mechanisms and for endogenous and exogenous components: some implications for research on aging
D Weinert
BIOLOGICAL RHYTHM RESEARCH (2005)
Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors
F Guillaumond et al.
JOURNAL OF BIOLOGICAL RHYTHMS (2005)
The molecular clock mediates leptin-regulated bone formation
LN Fu et al.
CELL (2005)
The antidepressant-like effect of the melatonin receptor ligand luzindole in mice during forced swimming requires expression of MT2 but not MT1 melatonin receptors
IC Sumaya et al.
JOURNAL OF PINEAL RESEARCH (2005)
Phase-shifts of 24-h rhythms of hormonal release and body temperature following early evening administration of the melatonin agonist agomelatine in healthy older men
R Leproult et al.
CLINICAL ENDOCRINOLOGY (2005)
Positive relationship between melatonin receptor type 1B polymorphism and rheumatoid factor in rheumatoid arthritis patients in the Korean population
EY Ha et al.
JOURNAL OF PINEAL RESEARCH (2005)
Melatonin, aging, and age-related diseases - Perspectives for prevention, intervention, and therapy
B Poeggeler
ENDOCRINE (2005)
Metabolic effects of melatonin on oxidative stress and diabetes Mellitus
S Nishida
ENDOCRINE (2005)
Functional MT1 and MT2 melatonin receptors in mammals
ML Dubocovich et al.
ENDOCRINE (2005)
Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers
ST Chen et al.
CARCINOGENESIS (2005)
Abnormal expression of Period 1 (PER1) in endometrial carcinoma
KT Yeh et al.
JOURNAL OF PATHOLOGY (2005)
Coupling of human circadian and cell cycles by the timeless protein
K Ünsal-Kaçmaz et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism
RM Sainz et al.
PROSTATE (2005)
Melatonin enhances leptin expression by rat adipocytes in the presence of insulin
MIC Alonso-Vale et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Shiftwork and metabolic risk factors of cardiovascular disease
M Ha et al.
JOURNAL OF OCCUPATIONAL HEALTH (2005)
Role of melatonin in neurodegenerative diseases
V Srinivasan et al.
NEUROTOXICITY RESEARCH (2005)
Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor I/insulin signaling and caloric restriction
KA Al-Regaiey et al.
ENDOCRINOLOGY (2005)
MT-1 melatonin receptor expression increases the antiproliferative effect of melatonin on S-91 murine melanoma cells
AL Kadekaro et al.
JOURNAL OF PINEAL RESEARCH (2004)
Maternal melatonin selectively inhibits cortisol production in the primate fetal adrenal gland
C Torres-Farfan et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Microarray analysis of postmortem temporal cortex from patients with schizophrenia
C Aston et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2004)
Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression
DK Welsh et al.
CURRENT BIOLOGY (2004)
Chronobiotic protocol and circadian sleep propensity index: New tools for clinical routine and research on melatonin and sleep
D Kunz
PHARMACOPSYCHIATRY (2004)
Lighting for the human circadian clock: recent research indicates that lighting has become a public health issue
SM Pauley
MEDICAL HYPOTHESES (2004)
Melatonin in patients with reduced REM sleep duration: Two randomized controlled trials
D Kunz et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin
DE Blask et al.
CARCINOGENESIS (2004)
Forced desynchronization of dual circadian oscillators within the rat suprachiasmatic nucleus
HO de la Iglesia et al.
CURRENT BIOLOGY (2004)
Central nervous determination of food storage - a daily switch from conservation to expenditure: implications for the metabolic syndrome
F Kreier et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2003)
Control mechanism of the circadian clock for timing of cell division in vivo
T Matsuo et al.
SCIENCE (2003)
Melatonin slowed the early biochemical progression of hormone-refractory prostate cancer in a patient whose prostate tumor tissue expressed MT1 receptor subtype
SYW Shiu et al.
JOURNAL OF PINEAL RESEARCH (2003)
The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways
MJ Millan et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Melatonin induces Cry1 expression in the pars tuberalis of the rat
H Dardente et al.
MOLECULAR BRAIN RESEARCH (2003)
Melatonin enhances lymphocyte proliferation and decreases the release of pituitary pro-opiomelanocortin-derived peptides in surgically traumatized rats
YS Huang et al.
NEUROSCIENCE LETTERS (2003)
Circadian clock-related polymorphisms in seasonal affective disorder and their relevance to diurnal preference
C Johansson et al.
NEUROPSYCHOPHARMACOLOGY (2003)
Health disorders of shift workers
A Knutsson
OCCUPATIONAL MEDICINE-OXFORD (2003)
Rhythmic histone acetylation underlies transcription in the mammalian circadian clock
JP Etchegaray et al.
NATURE (2003)
mt1 melatonin receptor in the primate adrenal gland: Inhibition of adrenocorticotropin-stimulated cortisol production by melatonin
C Torres-Farfan et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Circadian rhythms, oxidative stress, and antioxidative defense mechanisms
R Hardeland et al.
CHRONOBIOLOGY INTERNATIONAL (2003)
Effect of pinealectomy on plasma levels of insulin and leptin and on hepatic lipids in type 2 diabetic rats
S Nishida et al.
JOURNAL OF PINEAL RESEARCH (2003)
Melatonin rhythmicity: effect of age and Alzheimer's disease
DJ Skene et al.
EXPERIMENTAL GERONTOLOGY (2003)
Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity
DJ Long et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo
LN Fu et al.
CELL (2002)
Melatonin inhibits insulin secretion and decreases PKA levels without interfering with glucose metabolism in rat pancreatic islets
MC Picinato et al.
JOURNAL OF PINEAL RESEARCH (2002)
Rhythms of mammalian body temperature can sustain peripheral circadian clocks
SA Brown et al.
CURRENT BIOLOGY (2002)
Receptor (MT1) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1
E Peschke et al.
JOURNAL OF PINEAL RESEARCH (2002)
Coordination of circadian timing in mammals
SM Reppert et al.
NATURE (2002)
The other circadian system: Food as a zeitgeber
FK Stephan
JOURNAL OF BIOLOGICAL RHYTHMS (2002)
Melatonin and prostate cancer cell proliferation: Interplay with castration, epidermal growth factor, and androgen sensitivity
SWF Siu et al.
PROSTATE (2002)
Melatonin, longevity and health in the aged: An assessment
RJ Reiter et al.
FREE RADICAL RESEARCH (2002)
Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatonin
C von Gall et al.
NATURE NEUROSCIENCE (2002)
Melatonin inhibits estrogen receptor transactivation and cAMP levels in breast cancer cells
T Kiefer et al.
BREAST CANCER RESEARCH AND TREATMENT (2002)
Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of Delta-5 desaturase activity
S Nishida et al.
JOURNAL OF PINEAL RESEARCH (2002)
An association between idiopathic Parkinson's disease and polymorphisms of phase II detoxification enzymes:: Glutathione S-transferase M1 and quinone oxidoreductase 1 and 2
S Harada et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Functional expression of MT2 (Mel1b) melatonin receptors in human PAZ6 adipocytes
L Brydon et al.
ENDOCRINOLOGY (2001)
Inhibition of isoproterenol-induced lipolysis in rat inguinal adipocytes in vitro by physiological melatonin via a receptor-mediated mechanism
F Zalatan et al.
ENDOCRINOLOGY (2001)
Transcriptional repression of RORα activity in human breast cancer cells by melatonin
J Dal et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2001)
Effects of the circadian mutation 'tau' on the Harderian glands of Syrian hamsters
A Coto-Montes et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2001)
The pineal gland is not essential for circadian expression of rat period homologue (rper2) mRNA in the suprachiasmatic nucleus and peripheral tissues
K Oishi et al.
BRAIN RESEARCH (2000)
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
F Damiola et al.
GENES & DEVELOPMENT (2000)
Antiphase oscillation of the left and right suprachiasmatic nuclei
HO de la Iglesia et al.
SCIENCE (2000)
Resetting of circadian time peripheral tissues by glucocorticoid signaling
A Balsalobre et al.
SCIENCE (2000)
Pathways through which a regimen of melatonin and retinoic acid induces apoptosis in MCF-7 human breast cancer cells
K Eck-Enriquez et al.
BREAST CANCER RESEARCH AND TREATMENT (2000)
Melatonin decreases cell proliferation and transformation in a melatonin receptor-dependent manner
MP Jones et al.
CANCER LETTERS (2000)
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