期刊
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
卷 69, 期 4, 页码 779-783出版社
SPRINGER
DOI: 10.1007/s13105-013-0253-8
关键词
Diabetes; Hypoglycemia; Hepatoprotection; Streptozotocin; Rosmarinus officinalis
The present study examined the effect of water extract (200 mg/kg body weight) of Rosmarinus officinalis L. in streptozotocin (STZ)-induced diabetic rats for 21 days. The hepatoprotective effects were investigated in the liver tissues sections. There was a significant increase in serum liver biochemical parameters (aspartate aminotransferase, alanine transaminase, and alkaline phosphatase), accompanied by a significant decrease in the level of total protein and albumin in the STZ-induced rats when compared with that of the normal group. The high-dose treatment group (200 mg/kg body wt) significantly restored the elevated liver function enzymes near to normal. This study revealed that rosemary extracts exerted a hepatoprotective effect. The results indicate that the extract exhibits the protective effect on tissues and prove its potentials as an antidiabetic agent.
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