期刊
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
卷 2, 期 13, 页码 1612-1623出版社
AMER CHEMICAL SOC
DOI: 10.1021/jz200640x
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资金
- National Institutes of Health [R01CA115229]
- NSF MRSEC [DMR05-20020]
- National Science Foundation [CHE-0548188]
- Division Of Materials Research
- Direct For Mathematical & Physical Scien [1120901] Funding Source: National Science Foundation
The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial cell or protocell. Polymersomes are vesicles that can be made from synthetic, biological, or hybrid polymers and can be used as a model template to build cell-like structures. In this perspective, we discuss various areas where polymersomes have been used to mimic cell functions as well as areas in which the synthetic flexibility of polymersomes would make them ideal candidates for a biomembrane mimetic. Designing a polymersome that comprehensively displays the behaviors discussed herein has the potential to lead to the development of an autonomous, responsive particle that resembles the intelligence of a biological cell.
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