期刊
JOURNAL OF PHYSICAL CHEMISTRY C
卷 114, 期 28, 页码 12062-12068出版社
AMER CHEMICAL SOC
DOI: 10.1021/jp911539r
关键词
-
资金
- Australian Research Council [DP0558727]
- Curtin University
- John R. Oishei Foundation
- National Natural Science Foundation of China [20903066]
- Australian Research Council [DP0558727] Funding Source: Australian Research Council
Carbon nanoparticles become photoluminescent upon surface passivation with oligomeric polymer chains. In this work, the dependence of the carbon dots photoluminescent properties on the passivation polymer selection has been demonstrated by conjugating polyethylene glycol (PEG) chains, polyethylenimide-co-polyethylene glycol-co-polyethylenimide copolymer, and 4-armed PEG molecules, respectively. The cytotoxicity and cellular internalization of the resulting three types of photoluminescent nanoformulations of carbon dots, named CD2, CD3, and CD4, were evaluated. These nanoforinulations exhibited no apparent cytotoxicity on their own and were shown to successfully target cancer cells by conjugation with transferrin. The implication to the use of carbon dots as biocompatible optical nanoprobes for in vitro cancer diagnostics is discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据