期刊
JOURNAL OF PHARMACY AND PHARMACOLOGY
卷 62, 期 5, 页码 563-576出版社
WILEY
DOI: 10.1211/jpp.62.05.0002
关键词
apoptosis; diphenyl phosphonate; protease; proteolytic; serine
Objectives The role of proteases in the regulation of apoptosis is becoming increasingly apparent. Whilst many of these proteases are already characterised, some have yet to be identified. Traditionally caspases held the traditional role as the prime mediators of apoptosis; however, attention is now turning towards the contribution made by serine proteases. Key findings As unregulated apoptosis is implicated in various disease states, the emergence of this proteolytic family as apoptotic regulators offers novel and alterative opportunities for therapeutic targets. Summary This review presents a brief introduction and overview of proteases in general with particular attention given to those involved in apoptotic processing.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据