期刊
JOURNAL OF PHARMACEUTICAL SCIENCES
卷 107, 期 12, 页码 2969-2982出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.xphs.2018.08.010
关键词
powder X-ray diffraction; polymorphism; phase transformations; formulations; physical characterization
Since the discovery of X-ray diffraction and its potential to elucidate crystal symmetry, powder X-ray diffraction has found diverse applications in the field of pharmaceutical sciences. This review summarizes significant achievements of the technique during various stages of dosage form development. Improved understanding of the principle involved and development of automated hardware and reliable software have led to increased instrumental sensitivity and improved data analysis. These advances continue to expand the applications of powder X-ray diffraction to emerging research fields such as amorphous systems, mechanistic understanding of phase transformations, and Quality by Design in formulation development. (c) 2018 American Pharmacists Association (R). Published by Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据