4.6 Article

Identification of a novel sildenafil analogue in an adulterated herbal supplement

期刊

出版社

ELSEVIER SCIENCE BV
DOI: 10.1016/j.jpba.2011.10.001

关键词

Dietary supplement; Adulterants; Depiperazinothiosildenafil; NMR; MS

向作者/读者索取更多资源

iErect, a new dietary supplement marketed as 100% natural and sold over the Internet, was analyzed. It contains thiosildenafil, a sildenafil analogue already reported as an adulterant in herbal formulations, and a new compound whose structure was elucidated after isolation using NMR, MS and IR. It was named depiperazinothiosildenafil as it results from the hydrolytic cleavage of the S-N bond of the sulfonamide group of thiosildenafil. A capsule of iErect contains a very high amount (approximate to 220 mg) of thiosildenafil and mg of depiperazinothiosildenafil, which places consumers at risk for potentially serious side-effects. (C) 2011 Elsevier B.V. All rights reserved.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据