期刊
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
卷 53, 期 1, 页码 24-28出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jpba.2010.03.008
关键词
Health food; PDE-5 inhibitor; Adulterant; Aminotadalafil; NMR
An interaction product of aminotadalafil was isolated from an illegal health food product. The structure of the interaction product was elucidated by means of IR, NMR, and mass spectroscopy. The hitherto unknown compound was characterized as condensation product of aminotadalafil and hydroxymethylfuraldehyde and is probably the result of a drug-excipient incompatibility. (C) 2010 Published by Elsevier B.V.
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