期刊
JOURNAL OF PEPTIDE SCIENCE
卷 15, 期 10, 页码 629-633出版社
WILEY
DOI: 10.1002/psc.1158
关键词
solid-phase peptide synthesis; solvent; acetonitrile; racemization; oxyma
资金
- CICYT [CTQ2006-03794/BQU, CTQ2008-00177]
- Generalitat de Catalunya [2005SGR 00662]
- Barcelona Science Park
- Institute for Research in Biomedicine
This manuscript shows that ACN can be an excellent choice for the coupling of hindered amino acids as illustrated by the coupling of Fmoc-amino acids on free amino acids anchored on a BAL synthesis. Furthermore, ACN can be a good alternative for solid-phase peptide synthesis in the absence of DMF (washings, removal of Fmoc, and coupling). Copyright (C) 2009 European Peptide Society and John Wiley & Sons, Ltd.
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