期刊
JOURNAL OF PEDIATRICS
卷 159, 期 1, 页码 152-U184出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.jpeds.2011.03.057
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-
类别
资金
- National Institutes of Health [5T32AR007594-15, 5K24HD050387, 5U10HD037249, R01NS062756, M01-RR13297]
The pharmacokinetics of levetiracetam were determined prospectively in 18 neonates with seizures. Neonates were found to have lower clearance, higher volume of distribution, and a longer half-life as compared with older children and adults. Mild somnolence was the only adverse effect. (J Pediatr 2011; 159: 152-4)
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