期刊
JOURNAL OF PEDIATRICS
卷 155, 期 4, 页码 488-494出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.jpeds.2009.04.013
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资金
- MRC [MC_U105260558] Funding Source: UKRI
- Medical Research Council [MC_U105260558] Funding Source: Medline
- Medical Research Council [MC_U105260558] Funding Source: researchfish
Objectives To determine the efficacy of a neonatal parenting intervention for improving development in very preterm infants. Study design A cluster-randomized, controlled trial with a cross-over design and washout period was conducted in 6 neonatal centers. Two hundred thirty-three babies <32 weeks' gestation were recruited (intervention = 112; control = 121). Intervention families received weekly Parent Baby Interaction Programme (PBIP) sessions during neonatal intensive care unit admission and up to 6 weeks after discharge. Control families received standard care. All 195 infants remaining in the study at 24 months' corrected age were assessed by psychologists blinded to group allocation. Results There was no significant difference in Mental Development Index (-0.9 points; 95% CI, -5.0, 3.2) or Psychomotor Development Index (2.5; -3.3, 8.4) scores between the intervention and control groups and no significant effect of intervention on Mental Development Index or Psychomotor Development Index scores for subgroups dichotomized by gestational age (<28 weeks/>= 28 weeks), parity (1st/other child) or mother's cohabiting status (supported/unsupported). Conclusions There was no effect of PBIP on infant development at 2 years' corrected age. Parenting interventions may be better delivered after discharge or targeted for preterm infants with high biological and social risk. (J Pediatr 2009;155:488-94).
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