Multifocal leiomyosarcomatosis in a 6-year-old child with epidermodysplasia verruciformis and immune defect

Leiomyosarcoma and epidermodysplasia verruciformis are rarely encountered in children. The association of either leiomyosarcoma or epidermodysplasia verruciformis with immune deficiency has previously been documented. A 6-year-old girl, who has had multifocal leiomyosarcomatosis after the previous diagnoses of epidermodysplasia verruciformis and immune defect, represents an interesting association of these features. (C) 2009 Elsevier Inc. All rights reserved.