期刊
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
卷 56, 期 6, 页码 652-656出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MPG.0b013e318287e9d7
关键词
continuous feeding; enteral feeding; feeding; intermittent feeding; near-infrared spectroscopy; preterm infants; splanchnic oxygenation
Objectives: The aim of the present study was to compare the effects of continuous and intermittent bolus milk feeding on splanchnic regional oxygenation (rSO(2)S) in small-for-gestational age (SGA) and appropriate-for-gestational age (AGA) preterm infants. Methods: Infants with gestational age <32 weeks were prospectively studied by near-infrared spectroscopy. Each infant was given a milk bolus in similar to 10 minutes (intermittent feeding) followed after 3 hours by a 3-hour continuous feeding. rO(2)S and splanchnic fractional oxygen extraction ratio (FOES [S = splanchnic]) were recorded 30 minutes before (T-0) and 30 minutes after the beginning of bolus feeding (T-1), 30 minutes before (T-2), at the end (T-3), and 30 minutes after the continuous feeding period (T-4). Results: rSO(2)S increased at T-1 in both AGA and SGA groups, whereas FOES did not vary during the study period. Moreover, we found that rSO(2)S was higher and FOES was lower at T-1 and T-3 in the AGA than in the SGA group. Conclusions: Bolus milk feeding increases splanchnic oxygenation in both AGA and SGA infants, whereas continuous feeding does not. Splanchnic oxygenation is higher in AGA than in SGA infants both during bolus and continuous feeding. Continuous enteral feeding could help to limit the risk of hypoxic-ischemic gut damage in preterm infants in critical condition, especially in AGA infants.
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