期刊
JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY
卷 21, 期 6, 页码 323-328出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jpag.2007.09.008
关键词
Pubertal onset; Pubarche; Thelarche; Female puberty; Breast development; Pubic hair development in girls
资金
- The National Heart, Lung, and Blood Institute (NHLBI) [R01 HL38170]
- NHLBI Growth and Health, Cincinnati site [HC 55025]
Study Objective: To define anthropometric and hormonal differences in a group of black and white girls who began puberty with breast development alone (thelarche pathway) compared to those who began with pubic hair development alone (pubarche pathway), and test the hypothesis that pubarche may represent true pubertal development. Design: Longitudinal cohort seen annually for ten years. Setting: Recruited through elementary schools in Cincinnati, OH, and Richmond, CA; through HMO in Washington, DC. Participants: 9 years old, either Black or White, in the National Heart, Lung, and Blood Institute Growth and Health Study. Interventions: None; observational Study. Main Outcome Measures: Initial secondary sexual characteristic at onset Of puberty; anthropometric measures; hormone measures. Results: 478 of 1155 girls matured through a defined pathway. Age at onset of secondary Sexual characteristics was similar between pathways, although girls in the thelarche pathway had puberty at a somewhat younger age, and black participants entered at a significantly younger age. Height velocity was the same in both pathways, and in the pubertal range. DHEA-S levels at onset of puberty were significantly greater in girls in the pubarche pathway, but levels of estradiol and testosterone were not different. Age of menarche was different by race (younger in blacks) and pathway (younger in thelarche pathway). Conclusions: Given similar age and height velocities at onset of secondary sexual characteristics, these results suggest that pubarche, the development of pubic hair without breast development, may represent true pubertal maturation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据