相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Phosphatidylinositol-3-kinase pathway aberrations in gastric and colorectal cancer: Meta-analysis, co-occurrence and ethnic variation
Mei-Ling Chong et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
Molecular alterations of Ras-Raf-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt signaling pathways in colorectal cancers from a tertiary hospital at Kuala Lumpur, Malaysia
Wai Kien Yip et al.
APMIS (2013)
PIK3CA and PTEN Gene and Exon Mutation-Specific Clinicopathologic and Molecular Associations in Colorectal Cancer
Fiona L. Day et al.
CLINICAL CANCER RESEARCH (2013)
Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer Center
Marcel Wiesweg et al.
EUROPEAN JOURNAL OF CANCER (2013)
Pathology of Rodent Models of Intestinal Cancer: Progress Report and Recommendations
Mary Kay Washington et al.
GASTROENTEROLOGY (2013)
PTEN loss and KRAS activation cooperate in murine biliary tract malignancies
Victoria Marsh et al.
JOURNAL OF PATHOLOGY (2013)
Alterations in the EGFR pathway coincide in colorectal cancer and impact on prognosis
Jens Neumann et al.
VIRCHOWS ARCHIV (2013)
PTEN expression is consistent in colorectal cancer primaries and metastases and associates with patient survival
Chloe E. Atreya et al.
CANCER MEDICINE (2013)
Predictive role of multiple gene alterations in response to cetuximab in metastatic colorectal cancer: A single center study
Paola Ulivi et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2012)
Molecular Profiling of Patients with Colorectal Cancer and Matched Targeted Therapy in Phase I Clinical Trials
Rodrigo Dienstmann et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Therapeutic targeting of the phosphatidyl-inositol 3-kinase signaling pathway: novel targeted therapies and advances in the treatment of colorectal cancer
Ming Yu et al.
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2012)
Increased Detection Sensitivity for KRAS Mutations Enhances the Prediction of Anti-EGFR Monoclonal Antibody Resistance in Metastatic Colorectal Cancer
Francesca Molinari et al.
CLINICAL CANCER RESEARCH (2011)
Ink4a/Arf and Oncogene-Induced Senescence Prevent Tumor Progression during Alternative Colorectal Tumorigenesis
Moritz Bennecke et al.
CANCER CELL (2010)
PTEN Loss Accelerates KrasG12D-Induced Pancreatic Cancer Development
Reginald Hill et al.
CANCER RESEARCH (2010)
Clinicopathological significance of nuclear PTEN expression in colorectal adenocarcinoma
Ki-Seok Jang et al.
HISTOPATHOLOGY (2010)
Multi-Determinants Analysis of Molecular Alterations for Predicting Clinical Benefit to EGFR-Targeted Monoclonal Antibodies in Colorectal Cancer
Andrea Sartore-Bianchi et al.
PLOS ONE (2009)
Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer
Kentaro Iwanaga et al.
CANCER RESEARCH (2008)
Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation
Victoria Marsh et al.
NATURE GENETICS (2008)
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon
Kevin M. Haigis et al.
NATURE GENETICS (2008)
PTEN-deficient intestinal stem cells initiate intestinal polyposis
Xi C. He et al.
NATURE GENETICS (2007)
Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo
Owen J. Sansom et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Smad4 haploinsufficiency in mouse models for intestinal cancer
P Alberici et al.
ONCOGENE (2006)
Serrated adenoma of the colorectum and the DNA-methylator phenotype
JR Jass
NATURE CLINICAL PRACTICE ONCOLOGY (2005)
Epithelial hedgehog signals pattern the intestinal crypt-villus axis
BB Madison et al.
DEVELOPMENT (2005)
Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer
DM Dinulescu et al.
NATURE MEDICINE (2005)
Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers
A Goel et al.
CANCER RESEARCH (2004)
BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum
T Kambara et al.
GUT (2004)
Tissue-specific and inducible Cre-mediated recombination in the gut epithelium
F El Marjou et al.
GENESIS (2004)
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
OJ Sansom et al.
GENES & DEVELOPMENT (2004)
Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells
H Sheng et al.
GUT (2003)
Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context
C Guerra et al.
CANCER CELL (2003)
Analysis of K-ras codon 12 mutation in flat and nodular variants of serrated adenoma in the colon
Y Higashidani et al.
DISEASES OF THE COLON & RECTUM (2003)
Serrated adenomas and mixed polyposis caused by a splice acceptor deletion in the mouse Smad4 gene
P Hohenstein et al.
GENES CHROMOSOMES & CANCER (2003)
Emerging concepts in colorectal neoplasia
JR Jass et al.
GASTROENTEROLOGY (2002)
Oncogenic transformation induced by membrane-targeted Akt2 and Akt3
I Mende et al.
ONCOGENE (2001)
T cell-specific loss of Pten leads to defects in central and peripheral tolerance
A Suzuki et al.
IMMUNITY (2001)
分享论文
