期刊
JOURNAL OF PATHOLOGY
卷 226, 期 2, 页码 148-157出版社
WILEY
DOI: 10.1002/path.3029
关键词
chemokine; cytokine; inflammation; carcinogenesis; tumour-associated macrophages; metastases
资金
- Affitech AS
Chemokines (chemo-attractant cytokines) are a group of small proteins that act together with their cell surface receptors, in development, normal physiology and immune responses, to direct cells to specific locations throughout the body. Cancer cells acquire the ability to subvert the chemokine system, such that these molecules and their receptors become important regulators of cell movement into and out of the tumour microenvironment and major players in cancer biology. Copyright. (C) 2011 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
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