期刊
JOURNAL OF PAIN
卷 10, 期 7, 页码 663-693出版社
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.jpain.2009.04.001
关键词
Genetic association study; single nucleotide polymorphism; haplotype; population stratification; multiple test correction
资金
- Division of Intramural Research
- National Institute of Nursing Research
- National Institutes of Health [20892]
Understanding the genetic basis of human variations in pain is critical to elucidating the molecular basis of pain sensitivity, variable responses to analgesic drugs, and, ultimately, to individualized treatment of pain and improved public health. With the help of recently accumulated knowledge and advanced technologies, pain researchers hope to gain insight into genetic mechanisms of pain and eventually apply this knowledge to pain treatment. Perspective: We critically reviewed the published literature to examine the strength of evidence supporting genetic influences on clinical and human experimental pain. Based on this evidence and the experience of false associations that have occurred in other related disciplines, we provide recommendations for avoiding pitfalls in pain genetic research. (C) 2009 by the American Pain Society
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据