期刊
JOURNAL OF ORGANOMETALLIC CHEMISTRY
卷 749, 期 -, 页码 394-399出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jorganchem.2013.10.035
关键词
Silver(I) complexes; Pyridine; Benzimidazole; X-ray diffraction; Antimicrobial activity
资金
- Medical University of Lodz [503/3-016-02/503-01]
Three new silver(I) complexes of 4-(hydroxymethyl)pyridine (4-CH(2)OHpy), 2,6-di(hydroxymethyl)pyridine (2,6-di(CH2OH)py) and 2-(hydroxymethyl)benzimidazole (2-CH(2)OHbim) were synthesized. These complexes, with the general formula [Ag(L)(2)]NO3, were characterized by IR, NMR (H-1 and C-13) spectroscopy and elemental analysis. ESI-MS spectrometry was used in some cases. The crystal structure of [Ag(4-CH(2)OHpy)(2)]NO3 was determined by single crystal X-ray diffraction analysis. The complex demonstrates the slightly bent N1-Ag1-N2 coordination geometry (167.22(4)degrees) and consists of one nitrate anion and one silver ion coordinated by two 4-(hydroxymethyl) pyridine (4-CH(2)OHpy) ligands via N atoms. The series of three silver(I) complexes and the corresponding free ligands was tested for their antibacterial and antifungal activities, screened in vitro against Staphylococcus aureus ATCC 6538, Staphylococcus epidermidis ATCC 12228 and Candida albicans ATCC 10231. All the silver(I) complexes demonstrated considerable activity, especially against C. albicans (with MIC values 10-20 mg l(-1)). (C) 2013 Elsevier B. V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据