In-situ synthesis of a palladium-polyaniline hybrid catalyst for a Suzuki coupling reaction

Palladium-catalyzed cross-coupling reactions are one of the most frequently used synthetic tools for the construction of new carbon-carbon bonds in organic synthesis. The present study describes the use of palladium-polyaniline composite material as a catalyst for the Suzuki coupling of aryl halides. Palladium-polyaniline nanocomposite material was synthesized using an in-situ technique in which palladium acetate and aniline hydrochloride were used as the precursors of the composite. Electron microscopy imaging showed that the palladium particles were well-dispersed within the polymer matrix and were typically 3-5 nm in diameter. The metal-polymer composite material was used as a catalyst for the coupling of phenylboronic acid with aryl halides in the presence of an inorganic base and showed excellent yield with high TOF values. (C) 2010 Elsevier B.V. All rights reserved.