Trans-chelating ligands in palladium-catalyzed carbonylative coupling and methoxycarbonylation of aryl halides

The manuscript describes the use of a trans-chelated palladium complex derived from 1,8-bis-(4-(diphenylphosphino)phenyl)anthracene (1) and p-TolPdI(TMEDA) as a precatalyst in carbonylative Suzuki coupling and methoxycarbonylation of aryl iodides and bromides. The catalyst is active in 0.01-1 mol% loading and demonstrates highly selective transformations. The selectivity is attributed to the unique structural features of the trans-chelating ligands. (C) 2009 Elsevier B.V. All rights reserved.