4.7 Article

Iron-Catalyzed Acylation-Oxygenation of Terminal Alkenes for the Synthesis of Dihydrofurans Bearing a Quaternary Carbon

期刊

JOURNAL OF ORGANIC CHEMISTRY
卷 80, 期 1, 页码 698-704

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AMER CHEMICAL SOC
DOI: 10.1021/jo502535k

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资金

  1. State Key Laboratory of Heavy Oil Processing
  2. National Science Foundation of China [21272267]
  3. Fundamental Research Funds for the Central Universities
  4. Research Funds of Renmin University of China [10XNL017]
  5. Beijing National Laboratory for Molecular Sciences (BNLMS)

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Iron-catalyzed acylation-oxygenation of terminal alkenes is reported. Acyl radicals generated by the oxidation of aldehydes add to terminal alkenes and followed by intramolecular oxygenation give functionalized 2,3-dihydrofuran derivatives bearing a quaternary carbon.

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