Hypervalent Iodine-Mediated Oxygenation of N,N-Diaryl Tertiary Amines: Intramolecular Functionalization of sp3 C-H Bonds Adjacent to Nitrogen

An intramolecular C(sp(3))-O bond formation has been achieved via PhI(OAc)(2)/NaN3-mediated oxygenation of N,N-diaryl tertiary amines. The appealing features of this method include mild reaction conditions, absence of heavy-metal catalysts, and the direct intramolecular functionalization of sp(3) C-H bonds adjacent to nitrogen.