期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 79, 期 19, 页码 8984-8989出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo501221h
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资金
- National Natural Science Foundation of China [21472043, 21272070, 21072057]
- National Basic Research Program of China (973 Program) [2010CB126101]
- Twelfth Five-year Plan of China [2011BAE06B01-15]
A copper-free direct C-H ortho trifluoromethylation of electron-deficient 4-substituted acetanilides using Langlois reagent (NaSO2CF3) as the CF3 source in the presence of tert-butyl hydroperoxide (tBuOOH, TBHP) was developed.
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