期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 79, 期 9, 页码 4131-4136出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo500144z
关键词
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资金
- National Natural Science Foundation of China [21272200]
- Priority Academic Program Development of Jiangsu Higher Education Institutions
The functionalized spiro[indoline-3,2'-pyridine]-3',4',5',6'-tetracarboxylates were efficiently synthesized by BF3 center dot OEt2-catalyzed reactions of isatin-3-imines with acetylenedicarboxylates in methylene dichloride. Under similar conditions, the BF3 center dot OEt2-catalyzed three-component reactions of acetylenedicarboxylates, arylamines, and isatins afforded functionalized spiro[indoline-3,4'-pyridine]-2',3',5',6'-tetracarboxylates in moderate yields.
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