4.7 Article

Palladium-Catalyzed Cyanation of Aryl Halides with CuSCN

期刊

JOURNAL OF ORGANIC CHEMISTRY
卷 78, 期 6, 页码 2710-2714

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AMER CHEMICAL SOC
DOI: 10.1021/jo3025829

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资金

  1. National Natural Science Foundation of China [21272028, 21202013]
  2. Natural Science Foundation of Zhejiang Province [R4110294]
  3. Priority Academic Program Development of Jiangsu Higher Education Institutions

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A palladium-catalyzed cyanation of aryl halides and borons has been developed by employing cuprous thiocyanate as a safe cyanide source. This protocol avoids the use of a highly toxic cyanide source, providing aromatic nitriles in moderate to good yields with good functional tolerance.

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