4.7 Article

Synthesis of Tetramic Acid Derivatives via Intramolecular sp3 C-H Amination Mediated by Hypervalent Iodine(III) Reagents/Bronsted Acids

期刊

JOURNAL OF ORGANIC CHEMISTRY
卷 78, 期 2, 页码 733-737

出版社

AMER CHEMICAL SOC
DOI: 10.1021/jo302144w

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资金

  1. SRFDP [20110043110002]
  2. NNSFC [21172033]
  3. Fundamental Research Funds for the Central Universities [09ZDQD07, 11GJHZ001, 11QNJJ015]
  4. [NENU-10SSXT139]

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An efficient synthesis of tetramic acid derivatives was developed via intramolecular sp(3) C-H aminations of 1-acetyl N-aryl cyclopropane/cyclopentanecarboxamides in the presence of PhI(OPiv)(2) and CH3CH2COOH.

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