期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 77, 期 10, 页码 4854-4860出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo300725v
关键词
-
资金
- National Science Foundation [CHE-0847686]
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [0847686] Funding Source: National Science Foundation
Versatile trichloromethyl carbinols can be prepared in one pot from primary alcohols by treatment with Dess-Martin periodinane (DMP) in CHCl3 followed by introduction of commercially available 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD). A modification of the method was used to convert chiral primary alcohol (R)-(-)-2,2-dimethyl-1,3-dioxolane-4-methanol to the corresponding trichloromethyl carbinol with complete stereochemical fidelity, despite the reactant proceeding through a base-sensitive aldehyde intermediate.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据