4.7 Article

Diastereoselective Synthesis of Substituted Tetrahydrothiopyrans via (3,5)-Thionium-Ene Cyclization Reaction

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JOURNAL OF ORGANIC CHEMISTRY
卷 77, 期 5, 页码 2508-2512

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AMER CHEMICAL SOC
DOI: 10.1021/jo2023944

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  1. Council of Scientific and Industrial Research (CSIR), New Delhi [01(2332)/09/EMR-II]

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Tetrahydrothiopyrans have been efficiently synthesized in good yields with excellent diastereoselectivity from aldehydes and substituted 5-methylhex-4-ene-1-thiol via (3,5)-thionium-ene cyclization reaction mediated by boron trifluoride etherate.

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