期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 76, 期 19, 页码 8113-8116出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo201504h
关键词
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资金
- National Research Foundation (NRF)
- Korean Government [2011-0020477, 2011-0002316, 2011-0004321]
- Ministry of Education, Science and Technology [2011-0018396, 2010-0028294]
- Ajou university
- BK21 scholarship
We report two-photon Lysotrackers (CLT-blue and CLT-yellow) that can be excited by 750-840 nm femto-second laser pulses and emit at 470 and 550 nm, respectively. They can be easily loaded into cells and tissue slices for visualization of lysosomes in live cells and tissues for a long period of time through two-photon microscopy. When combined with appropriate two-photon probes for other biological targets, these novel probes would greatly facilitate the two-photon microscopy colocalization experiments.
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