期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 76, 期 18, 页码 7608-7613出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo2013725
关键词
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资金
- FWO (Fund for Scientific Research-Flanders (Belgium))
- University of Leuven
- FWO
- China Scholarship Council
A novel and efficient microwave-assisted decarboxylative three-component coupling of a 2-oxoacetic acid, an amine, and an alkyne (OA(2)-coulpling) has been developed. This new multicomponent coupling constitutes an efficient approach for the synthesis of polysubstituted propargylamines in the presence of a catalytic amount of copper(I) catalyst.
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