4.7 Article

Regio- and Stereoselective Multisubstituted Enol Ester Synthesis

期刊

JOURNAL OF ORGANIC CHEMISTRY
卷 76, 期 21, 页码 9133-9138

出版社

AMER CHEMICAL SOC
DOI: 10.1021/jo201609r

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资金

  1. JSPS KAKENHI [23590032]
  2. Grants-in-Aid for Scientific Research [22390001, 23590032] Funding Source: KAKEN

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Regio- and stereoselective cohalogenation of alkynes with NXS (X = Br, I) was achieved, and the stereoselectivity of the resulting alkenes was dependent on the substituent on the alkyne. Cohalogenation and successive cross-coupling gave multisubstituted enol esters in a one-pot process.

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