期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 76, 期 1, 页码 195-200出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo1019442
关键词
-
资金
- ANR [BLAN09-0082-01, PCV07_185434]
- European Union [PIIF-2009-237149]
- ADB
- ARC
The synthesis of quinoline-derived helically folded aromatic oligoamides functionalized by various chiral functions at their N-terminus is reported. When a (1S)-(-)-camphanyl moiety was introduced, it was found that helix handedness was completely shifted to right-handed helicity (de > 99%), in both protic and nonprotic solvents. The absolute helical sense and the de values were unambiguously characterized by using H-1 NMR, circular dichroism (CD), and X-ray crystallography. The crystal structure of these compounds allowed us to propose a rationale for the efficiency of helix handedness induction based on a combination of steric factors and intramolecular hydrogen bonding.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据