4.7 Article

Palladium-Catalyzed Direct and Regioselective C-H Bond Functionalization/Oxidative Acetoxylation of Indoles

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JOURNAL OF ORGANIC CHEMISTRY
卷 76, 期 1, 页码 80-84

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AMER CHEMICAL SOC
DOI: 10.1021/jo101584k

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  1. Research Grants Council of Hong Kong [CERG: PolyU5008/08P]
  2. PolyU [A-PG 13]
  3. University Grants Committee Areas of Excellence Scheme [AoE/P-10/01]

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The first general examples of palladium-catalyzed direct and selective oxidative C3-acetoxylation of indoles are presented. The mild reaction conditions (70 degrees C and with weak base, KOAc) in this indole C-H-acetoxylation are notable.

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