期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 75, 期 18, 页码 6271-6274出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo1011448
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资金
- School of Chemistry at the University of Nottingham
A nucleophilic catalysis method providing a concise synthesis of di-, tri-, and tetrasubstituted pyrroles is described. This regioselective one-pot method relies on nucleophilic catalysis of the intermolecular addition of oximes to activated alkynes and thermal rearrangement of the in situ generated O-vinyl oximes to form pyrroles that contain a functional group handle at the C3/C4 position.
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