期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 75, 期 10, 页码 3488-3491出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo100392x
关键词
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A straightforward and efficient one-step procedure for the synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters is described, The simple reductive cyclization is carried out by treating various substituted o-nitrobenzaldehydes with inexpensive, commercially available 3,3-diethoxypropionic acid ethyl ester and SnCl(2)center dot 2H(2)O in refluxing ethanol.
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