4.7 Article

Au/Ag-Cocatalyzed Aldoximes to Amides Rearrangement under Solvent- and Acid-Free Conditions

期刊

JOURNAL OF ORGANIC CHEMISTRY
卷 75, 期 4, 页码 1197-1202

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AMER CHEMICAL SOC
DOI: 10.1021/jo902461a

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资金

  1. University of St. Andrews
  2. ICIQ Foundation
  3. ICREA
  4. ERC (FUNCAT)
  5. Ministerio de Educacion y Ciencia (Spain)
  6. EPSRC (UK)
  7. AGAUR for a fellowship [2007171_A 01466, 2008FI 01047]
  8. Ministerio de Ciencia y Innovacion for a Torres Quevedo fellowship
  9. EPSRC [EP/H015418/1] Funding Source: UKRI
  10. Engineering and Physical Sciences Research Council [EP/H015418/1] Funding Source: researchfish

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The gold/silver-cocatalyzed conversion of aldoximes into primary amides is reported. The reaction, which proceeds under neat and acid-free conditions, allows for the conversion of a range of aldoximes, and is a rare example of cooperative catalysis involving well-defined gold species.

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