期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 75, 期 23, 页码 8275-8278出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo101503p
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资金
- Islamic Azad University, Shahreza Branch
- Department of Chemistry, The University of Sheffield
Addition of (S)-(+)-tert-butyl 2-(iodomethyl)pyrrolidine-1-carboxylate to activated zinc, aryl halides, and a catalyst derived from Pd-2(dba)(3) (2.5 mol %) and SPhos (5 mol %) in DMF allows trapping of the corresponding organozinc reagent, with formation of Boc-protected 2-benzylpyrrolidines (20-72%).
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