Aqueous Iodine(III)-Mediated Stereoselective Oxidative Cyclization for the Synthesis of Functionalized Fused Dihydrofuran Derivatives

An efficient aqueous oxidative cyclization mediated by the combination of iodosobenzene with tetra-(n-butyl)-ammonium iodide provides a new convenient and useful route to functionalized fused dihydrofuran derivatives in moderate to excellent yields with high diastereoselectivities.