期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 75, 期 22, 页码 7939-7941出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo1016822
关键词
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资金
- State of Florida
- NIH [1R03DA025850-01A1, A N 5P41GM081261-03 Houghten, 3P41GM079590-03S1 Houghten]
Macrocyclization via an efficient high-yielding solid-phase intramolecular thioalkylation reaction is described The reaction of S-nucleophiles with newly generated N-terminal 4-chloromethyl thiazoles led to the desired macrocyclization products 5 in high purities and good overall yields
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