期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 75, 期 12, 页码 4218-4223出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo1006762
关键词
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资金
- Ministry of Education, Culture, Sports, Science, and Technology of Japan
- Open Research Center
- Takeda Science Foundation
Two new bisindole alkaloids, bisnicalaterines B and C (1 and 2) consisting of an eburnane and a corynanthe type of skeletons, were isolated from the bark of Hunteria zeylanica. Their absolute structures were determined by combination of NMR, CD, and computational methods, and each of them was shown to be in an atropisomeric relationship. Bisnicalaterines B and C (1 and 2) showed potent vasorelaxant activity on isolated rat aorta.
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