期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 75, 期 7, 页码 2382-2388出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo100225r
关键词
-
资金
- National Natural Science Foundation of China [20832006]
- Ministry of Science and Technology of China [2009ZX-09501-006]
- Beijing Municipal Commission of Education
1-Thiocarbamoyl imidazo[1,5-a]pyridinium inner salts, which were obtained readily from the addition of C,N-substituted heterocyclic carbenes imidazo[1,5-a]pyridine-1-ylidenes to Isothiocyanates, are powerful ambident nucleophilic zwitterions. They acted as nitrogen nucleophiles toward ethyl propiolate to produce polyfunctionalized pyrrole derivatives in high yields. When treated with dimethyl acetylenedicarboxylate, they behaved exclusively as sulfur nucleophiles to afford fully substituted thiophenes in excellent yields. This work provides highly efficient orthogonal synthesis of polyfunctionalized pyrroles and thiophenes that were not easily obtained by other chemical means.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据