Expeditive synthesis of glycodendrimer scaffolds based on versatile TRIS and mannoside derivatives

A new family of glycodendrimer scaffolds containing 12 and 18 peripheral alpha-D-mannopyranosidic units has been synthesized by Cu(I)-catalyzed [1,3]-dipolar cycloadditions using sulfurated dendritic scaffolds bearing alkyne functionalities and novel TRIS derivatives.