4.7 Article

Efficient synthesis of fluoren-9-ones by the palladium-catalyzed annulation of arynes by 2-haloarenecarboxaldehydes

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JOURNAL OF ORGANIC CHEMISTRY
卷 73, 期 17, 页码 6679-6685

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AMER CHEMICAL SOC
DOI: 10.1021/jo8009215

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资金

  1. National Institute of General Medical Sciences [R01 GM070620, R01 GM079593]
  2. National Institutes of Health Kansas University Center of Excellence [P50 GM069663]
  3. National Science Foundation

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Fluoren-9-ones and derivatives are readily prepared in good yields by the annulation of in situ generated arynes by 2-haloarenecarboxaldehydes in the presence of a palladium catalyst.

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