期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 73, 期 15, 页码 6041-6044出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo800941h
关键词
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The enantioselective carbolithiation of ortho-substituted (E)-beta-methylstyrenes provides access to chiral lithiated intermediates with broad synthetic potential. Specifically, beta-methylstyrenes with o-aminomethyl, ether, and oxazoline groups have been employed in the synthesis of chiral aromatics and heteroaromatics such as isoquinolines, isoquinolinones, benzofurans, and isobenzofuranones.
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