期刊
JOURNAL OF ORAL REHABILITATION
卷 40, 期 6, 页码 413-417出版社
WILEY
DOI: 10.1111/joor.12049
关键词
bruxism; clinical trial; therapeutic; child; sleep disorder; hydroxyzine
资金
- Shiraz University of Medical Sciences [2796]
This is a randomised placebo-controlled clinical trial investigating the efficacy of hydroxyzine for treating parent-reported sleep bruxism in children. Participants of this trial were 30 patients randomly allocated to one of the two groups in a ratio of 1:2. One group received hydroxyzine and the other group received placebo. The outcome measures were Visual Analogue Scale test and Clinical Global Severity scale. Assessments occurred at baseline and at the end of week 4. The side effects of drugs were assessed using a checklist. The number of children in the hydroxyzine and placebo groups was 21 and 9, respectively. The mean age of children in the hydroxyzine and placebo groups was 8 center dot 4(s.d.=3 center dot 3) and 6 center dot 5(s.d.=1 center dot 5) years, respectively. Hydroxyzine more than placebo decreased bruxism score (3 center dot 8 versus 2 center dot 2). No serious adverse effect was reported. Current evidence support that hydroxyzine is effective and well tolerated for treating bruxism in children.
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